Antifungal activities of Zerovalent Cobalt and Nickel nanocomposites Integrated with Crosslinked Chitosan-Humic acid against some Candida species

Authors

  • C.A. Akinremi
  • N. N. Omos
  • S. Adewuyi
  • M. A. Idowu
  • S. A. Amolegbe
  • A. O. Atayese

Abstract

Zerovalent Cobalt and Nickel nanocomposites with crosslinked Chitosan-Humic acid were synthesized. Humic acid was used for intramolecular cross-linking of the chitosan linear chains to increase the active sites on the chitosan biopolymer which was further used as stabilizer to synthesize zerovalent metal nanoparticles by the reduction of metal chlorides with sodium borohydride. Characterization of the products was carried out using Infrared spectrophotometer, Scanning Electron Microscope (SEM), Transmission Electron Microscope (TEM) and Powder X-Ray Diffractometer (PXRD). Chitosan, humic acid and the nanocomposites were investigated for antifungal activity against four Candida species (C. albicans, C. glabrata, C. tropicalis and C. parapsilosis). Significant antifungal activity was observed with the highest against Candida albicans.Keywords: Chitosan, Humic acid, Antifungal property, Metal nanoparticle

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Published

2018-02-03

How to Cite

Akinremi, C., Omos, N. N., Adewuyi, S., Idowu, M. A., Amolegbe, S. A., & Atayese, A. O. (2018). Antifungal activities of Zerovalent Cobalt and Nickel nanocomposites Integrated with Crosslinked Chitosan-Humic acid against some Candida species. Journal of Chemical Society of Nigeria, 43(1). Retrieved from http://journals.chemsociety.org.ng/index.php/jcsn/article/view/141

Issue

Vol. 43 No. 1 (2018)

Section

Articles

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Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution (CC-BY) 4.0 License that allows others to share the work with an acknowledgment of the work’s authorship and initial publication in this journal.

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