STUDIES ON Dacryodes edulis III: ISOLATION AND CHARACTERIZATION OF GALLIC ACID FROM METHANOLIC EXTRACT OF RAW (UNTREATED) SEEDS OF Dacryodes edulis AND ITS ANTIMICROBIAL PROPERTIES

T. A. Tor-Anyiin, J. O. Igoli, J. O. Igoli, J. N. Anyam

Abstract


In continuation of our studies on seeds of D. edulis, the methanol extract of raw/untreated seeds of Dacroydes edulis was subjected to vacuum liquid chromatography (VLC) on silica gel. Needle shaped crystals were observed. Fractions were monitored using TLC and similar fractions were combined and further purified using Sephadex LH-20 column (gel filtration chromatographic technique). This led to the isolation of gallic acid, as needle shaped crystals which was characterized by FT-IR, IH and13C-NMR spectra data as well as comparison with reported data. Gallic acid showed moderate antibacterial and antifungal activities. This is the first report on isolation of gallic acid from the seeds of Dacryodes edulis.

 Key Words: Dacryodes edulis, Raw/Untreated   seeds, Methanol extract, Gallic acid, Antimicrobial activity.

 


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Chemical Society of Nigeria