Synthesis, Characterization and Bioactivity of N,N’-bis[2-(5-bromo-7-azabenzimidazol-1-yl)-2-oxoethyl]ethylene-1,3-diamine and the –cyclohexyl-1,2-diamine analogue.

Authors

  • K. A. Oluwafemi

Abstract

 N,N’-bis[2-(5-bromo-7-azabenzimidazol-1-yl)-2-oxoethyl]ethylene-1,3-diamine  and the –cyclohexyl- 1,2-diamine analogue were synthesized from 7-aza-5-bromobenzimidazole. Their effect on human cervix adenocarcinoma cells was examined and the results indicated that the two novel compounds were not cytotoxic. Azabenzimidazoles; Akylation; HeLa cells; Cytotoxicity; NMR

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Published

2020-03-30

How to Cite

Oluwafemi, K. A. (2020). Synthesis, Characterization and Bioactivity of N,N’-bis[2-(5-bromo-7-azabenzimidazol-1-yl)-2-oxoethyl]ethylene-1,3-diamine and the –cyclohexyl-1,2-diamine analogue. Journal of Chemical Society of Nigeria, 45(2). Retrieved from http://journals.chemsociety.org.ng/index.php/jcsn/article/view/445

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