Novel synthesis of metal complexes of palmitoyl thioureas and their antimicrobial activities

Authors

  • J. N. Asegbeloyin
  • E. E. Oyeka
  • I. Babahan
  • O. Okpareke

Abstract

Novel Ni(II) and Cu(II) complexes of N-(diethylamin-4-ylcarbonothioyl)palmitamide [HL1] and N-(morpholin-4-ylcarbonothioyl)palmitamide [HL2] have been synthesized and characterized by elemental analysis, FT-IR, UV-VIS, 1H NMR and mass spectroscopy. Ni(II) and Cu(II)  complexes were isolated as four coordinated ML2 and six coordinated ML2(H2O)2 molecules respectively. The ligands coordinated as monoanions after deprotonation. In vitro screening of HL1, HL2 and their metal complexes against some bacteria and yeasts revealed that the complexes showed better antimicrobial property than the organic molecules.Keywords: Palmitoyl thioureas, synthesis, metal complexes, antimicrobial studies  

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Published

2018-07-24

How to Cite

Asegbeloyin, J. N., Oyeka, E. E., Babahan, I., & Okpareke, O. (2018). Novel synthesis of metal complexes of palmitoyl thioureas and their antimicrobial activities. Journal of Chemical Society of Nigeria, 43(3). Retrieved from https://journals.chemsociety.org.ng/index.php/jcsn/article/view/206

Issue

Vol. 43 No. 3 (2018)

Section

Articles

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Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution (CC-BY) 4.0 License that allows others to share the work with an acknowledgment of the work’s authorship and initial publication in this journal.