SPECTROSCOPIC AND ANTIMICROBIAL STUDIES OF METAL COMPLEXES OF CROSSLINKED CHITOSAN-CURCUMIN

Authors

  • C.A Akinremi
  • A. M Adeyemi
  • A.O Adebayo
  • L.O Abimbola
  • M. A. Olusola

Abstract

Potential uses of metal complexes of curcumin and chitosan as new antimicrobial drugs were investigated. The cross-linking of chitosan and curcumin as well as their complexation with cobalt, nickel and silver ions were carried out in solution. Metal complexes of the individual ligands were also prepared. All the products and ligands were characterised using micro analytical techniques, UV-Vis and FTIR spectroscopy. Spectra from the UV-Vis and FTIR confirmed the interaction of the metals with the single and mixed ligands. The products and constituents were tested against Staphylococcus aureus and Escherichia coli using the plate agar diffusion method. The metal complexes showed comparable activities against the microbes with better activity against Staphylococcus aureus. Keywords: Chitosan, Curcumin, Crosslinking, Antimicrobial 

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Published

2018-07-24

How to Cite

Akinremi, C., Adeyemi, A. M., Adebayo, A., Abimbola, L., & Olusola, M. A. (2018). SPECTROSCOPIC AND ANTIMICROBIAL STUDIES OF METAL COMPLEXES OF CROSSLINKED CHITOSAN-CURCUMIN. Journal of Chemical Society of Nigeria, 43(3). Retrieved from https://journals.chemsociety.org.ng/index.php/jcsn/article/view/209

Issue

Vol. 43 No. 3 (2018)

Section

Articles

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Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution (CC-BY) 4.0 License that allows others to share the work with an acknowledgment of the work’s authorship and initial publication in this journal.