SYNTHESIS, CHARACTERIZATION AND INSECT REPELLANT ACTIVITY OF SOME CHALCONE DERIVATIVES

Authors

  • A. E. Aiwonegbe
  • J. U. Iyasel

DOI:

https://doi.org/10.46602/jcsn.v47i1.694

Abstract

Four chalcone derivatives: 1,3-diphenylprop-2-en-1-one (AA1), 1-(4-nitrophenyl)-3-phenylprop-2-en-1-one (AA2), 1-phenyl-3-(3,4,5- trimethoxyphenyl)prop-2-en-1-one (AA3) and 1-(4-nitrophenyl)-3-(3,4,5-trimethoxyphenyl) prop-2-en-1-one (AA4) were synthesized by Claisen-Schmidt condensation of functionalized acetophenone with benzaldehyde derivatives. The synthesized compounds were characterized by spectroscopic procedures (IR, 1H-NMR, 13C-NMR and GC-MS). The compounds were obtained in good yield and their purity was ascertained with TLC and by melting point. The preliminary insect repellant activity of the compounds on Callosobruchus maculatus (cowpea weevil) was also determined. Chalcones AA1, AA3 and AA4 were highly repellant, moderately repellant and highly repellant respectively while AA2 displayed insecticidal activity.

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Published

2022-02-27

How to Cite

Aiwonegbe, A. E. ., & Iyasel, J. U. . (2022). SYNTHESIS, CHARACTERIZATION AND INSECT REPELLANT ACTIVITY OF SOME CHALCONE DERIVATIVES . Journal of Chemical Society of Nigeria, 47(1). https://doi.org/10.46602/jcsn.v47i1.694

Issue

Vol. 47 No. 1 (2022): J. Chem. Soc. Nigeria

Section

Articles

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Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution (CC-BY) 4.0 License that allows others to share the work with an acknowledgment of the work’s authorship and initial publication in this journal.