PHYTOCHEMICAL SCREENING, QUANTITATIVE ANALYSIS AND ANTIMICROBIAL ACTIVITY OF THE PLANT EXTRACT OF Hemizygia welwitschii
AbstractStudies in this paper is focused on investigating the antimicrobial activity of the leaves extract of Hemizygia welwitschii plant. The chemical constituent of the extract was determined via phytochemical analysis. Thereafter, the antimicrobial screening of the extract was carried out on Staphylococcus aureus and Escherichia coli using Mueller Hinton agar method. The outcome of the phytochemical analysis reveals the presence of saponins (4.4 g), steroids (174 mg/100g), flavonoids (14.2 g), tannins (511 mg/100g), Phenol (2.04 mg/g), alkaloid (9.8 g) and anthroaquinones (3.6 g) in the extracts. Also, the result of the antimicrobial screening showed that the extract is more active against Staphylococcus aureus than Escherichia coli. Significant Inhibition of Staphylococcus aureus was observed at a concentration of 500 mg/ml. Thus, the continued use of the extract in the treatment of Staphylococcus aureus related diseases should be encouraged.
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