Synthesis of 1, 1-bis(2-carbamoylguanidino)furan-2- ylmethane

Authors

  • K. J. Orie
  • R. I. Ngochindo a:1:{s:9:"biography";a:1:{s:5:"en_US";s:0:"";}}
  • O. J. Abayeh

Abstract

This study reports the synthesis of 1,1-bis(2-Carbamoylguanidino)furan-2-ylmethane,in a 2 step synthesis. The first step involves the coupling of furfural with urea to obtain 1-((2- carbamoylguanidino)(furan-2-ylmethyl)urea, which was subsequently refluxed with more urea in ethanol for 1 hour to afford the product. Both intermediate and product were characterized by GC- MS, IR, 1H-NMR, 13C-NMR, 1H-1H COSY, HSQC, and DEPT. The product obtained from the study is a novel compound with possible outlets in the pharmaceutical and chemical industries.Keywords: Furfural, Urea, 1-((2-carbamoylguanidino)(furan-2-ylmethyl)urea, 1,1-bis(2- Carbamoylguanidino)furan-2-ylmethane

Downloads

Published

2019-03-25

How to Cite

Orie, K. J., Ngochindo, R. I., & Abayeh, O. J. (2019). Synthesis of 1, 1-bis(2-carbamoylguanidino)furan-2- ylmethane. Journal of Chemical Society of Nigeria, 44(2). Retrieved from https://journals.chemsociety.org.ng/index.php/jcsn/article/view/267

Issue

Vol. 44 No. 2 (2019): JCSN

Section

Articles

License

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution (CC-BY) 4.0 License that allows others to share the work with an acknowledgment of the work’s authorship and initial publication in this journal.

Most read articles by the same author(s)