SYNTHESIS, CHARACTERIZATION AND INVITRO-ANTI-MICROBIAL ACTIVITIES OF 3- NITRO –N- (3-NITROBENZYLIDINE) ANILINE SCHIFF BASE COMPLEXES OF COBALT (II) AND CU (II)
DOI:
https://doi.org/10.46602/jcsn.v49i5.1008Abstract
Schiff base derived from an equimolar amount of 3-nitrobenzaldehyde with P-nitro aniline was synthesized. The Schiff base was subsequently reacted with Cobalt (II) chloride and Copper (II) chloride to form the metal complexes. The compounds were characterized using FTIR, UV-visible, melting point/decomposition and solubility test. The solubility test of the compounds showed that they are soluble in most organic solvents and the melting point of the schiff base ligand was found to be 147.8 oC and the decomposition temperature of the Cobalt (II) and Copper (II) were found to be 158.8oC and 157.9oC for the Cobalt (II) and Copper (II) complexes respectively. The UV and the IR spectroscopy confirmed the formation of complex. The antimicrobial studies of the synthesized ligands and their Cobalt (II) and Copper (II) metal complexes were carried out against Aspergillus, Gram positive bacteria Staphylococcus aureus and Gram-negative bacteria Escherichia coli. The results indicated that the metal complexes were more active than the ligand but less active compared to standard drugs (ciprofloxacin and fluconazole).Downloads
Published
2024-11-08
How to Cite
Bello, N. M. ., Yusif, A. ., Ebune, A. O. ., & Ahmad, K. B. . (2024). SYNTHESIS, CHARACTERIZATION AND INVITRO-ANTI-MICROBIAL ACTIVITIES OF 3- NITRO –N- (3-NITROBENZYLIDINE) ANILINE SCHIFF BASE COMPLEXES OF COBALT (II) AND CU (II) . Journal of Chemical Society of Nigeria, 49(5). https://doi.org/10.46602/jcsn.v49i5.1008
Issue
Section
Articles
License
Copyright (c) 2024 N. M. Bello, A. Yusif, A. O. Ebune, K. B. Ahmad
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution (CC-BY) 4.0 License that allows others to share the work with an acknowledgment of the work’s authorship and initial publication in this journal.